Now that we have the audio file, we need to decide what we are going to animate with. If like me you decided to specialise in animation then you may not be able to model and rig your own character. That's ok though because there are a multitude of rigs out there built by clever people who do have those skills and are willing to share their generic/practice rigs for us animators to use. Just don't go using them for commercial or profit making films.
Here are some of the rigs I found at 11 second club. They have a great website where you can enter a character animation competition each month. Some rigs are better than others, the three in the middle of the above picture are the ones I have chosen. Partly because I have used them before and know they work well and partly because they fit the characters of the dialogue.
As you can see I have chosen to use MAYA. This is the program I am most comfortable with but there are a multitude of choices around. The best bet is to decide based on the industry standard software of the field you want to crack into. High end character animation almost always uses MAYA. Games animation would be 3DS Max. Investigate the companies you want to work at and see what they use.